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Boaz is an ugly creature that swipes at you with her claws, bites and spews out poisonous goo that knocks Kurtis off his feet. Save your game before trying to defeat her.
Shoot her 4 or 5 times in the face until she starts shooting out goo from her sides. You’ll need to destroy all four of the goo sacs. There’s two on each side. When she stops flip to one of her sides and shoot the one that Kurtis targets. Once it’s destroyed you’ll have to manually switch targets (End on the PC) to shoot the other one.
Repeat this process for the other side and the creature will lay down. Watch the video above if you’re not sure how to do it.
The fight isn’t over yet! Boaz will transform into a flying creature and attack. Just shoot straight at her until she falls. Approach the body and wait a few seconds for the cut-scene to trigger.